Lots of really great stories/biographies about the women who worked in the far north in a profession that still struggles for mainstream legitimacy or respectability. In the early times, the women made their own money and often owned hotels and shops among the non-sexworkers. Miners often left their gold with them for safekeeping. It seems their district gave to the town and the town gave to them after fires and other tragedies. Maybe they were better off and more accepted than today's sex workers - in some ways. It's complicated. 

This is more about those following the gold rush who pushed in to Yukon and Alaska Territory and staked claims, so unfortunately you won't get any clear idea about how the native people fared. I would like to read those accounts though.